Most medications in the United States prior to 1880 came from England and Europe where heads of state regularly gave “patents” to their favorite manufacturers. “Patent medicines” are those with disclosed ingredients and were initially imported with great success since production in the colonies was limited.
Vin Mariana (with cocaine)
Vin Mariani was a very popular wine and coca product invented by Corsican chemist Angelo Mariani that was sold in both Europe and the United States. It was so popular that American John Pemberton manufactured a similar product that he called French Wine Coca. Because of the temerance movement at the time, Pemberton removed the alcohol and his product evolved into the modern day Coca Cola.
Vin Mariani with endorsement of the Pope
Vin Mariani received numerous testimonials from the rich and famous, including Thomas Edison, Queen Victoria, and three Popes. In fact, Pope Leo XIII awarded the coca containing Vin Mariani a gold medal “in recognition of benefits received from the use of Mariani’s tonic.”